Technology Bundle ID
TAB-2743
Molecular Detection and Viral-Load Quantification for HIV-1 Groups M, N and O, and Simian Immunodeficiency Virus-cpz (SIVcpz)
Linked ID
E-271-2013-0
Lead Inventors
Renu Lal (CDC)
Co-Inventors
Danuta Pieniazek (CDC)
Development Stages
Pre-Clinical (in vitro)
Development Status
- In vitro data available
- In situ data available (on-site)
ICs
CDC
This invention provides materials, methods, and assays for detecting HIV-1 groups M and O and optionally HIV-1 group N and simian immunodeficiency virus-cpz (SIV-cpz). Specific nucleic acid primers for hybridization, amplification, and detection of HIV-1 are also provided for. The nucleic acid amplification assays can detect small concentrations of HIV-1 and are also useful for quantitative examinations of viral load concentrations within biological samples.
Commercial Applications
- Blood and plasma donation screening
- Diagnostic detection of HIV-1
- Public health programs
- Monitoring HIV treatment and disease inhibition/progression
Competitive Advantages
- Broad-use, generic viral detection for groups M, N and O HIV-1, and also SIVcpz
- Requires minute quantities of virus for use, making this assay ideal for confirmation of early-stage infection
- Sensitive and highly specific
- Easily formulated for kits
- Established efficacy in patient samples
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