Technology Bundle ID
TAB-1174

AAV4 Vector and Uses Thereof

Applications
Linked ID
E-071-2000-0
Lead Inventors
John Chiorini (NHLBI)
Co-Inventors
Beverly Davidson (EM)
Brian Safer (NHLBI)
Robert Kotin (NHLBI)
Disease Areas
ICs
The invention described and claimed in this patent application relates to the delivery of heterologous nucleic acids or genes to particular target cells. In particular, the application relates to methods of delivering a heterologous nucleic acid or gene of interest to particular target cells using Adeno-Associated Virus of serotype 4 (AAV4). The particular target cells identified are the ependymal cells of the brain. The methods described herein may be useful in carrying out gene therapy for diseases of the brain or central nervous system.

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