Technology ID
TAB-4632
Real-time RT-PCR Assay for Detection and Characterization of North American Lineage of A/H7 Influenza Viruses
E-Numbers
E-048-2017-0
Lead Inventor
Liu, Ji
Lead IC
CDC
Co-Inventors
Shu, Bo
Lindstrom, Stephen
Wu, Kai-Hui
Warnes, Christine
Berman, LaShondra
ICs
CDC
Applications
Therapeutics
Research Materials
Therapeutic Areas
Infectious Disease
Development Stages
Pre-Clinical (in vitro)
This technology includes an updated North American Lineage H7 (N.A H7) real-time RT-PCR assay is designed for specific detection and characterization of North American lineage of A/H7 influenza viruses. Since 1995, poultry infection with N.A lineage influenza A/H7 viruses has been greatly increasing. The outbreaks of N.A A/H7 viruses in poultry as well as wild birds occurred many times in Canada, Mexico and USA; meanwhile a number of human infection caused by N.A A/H7 viruses have been confirmed following exposure to infected poultry. This assay was optimized in order to facilitate surveillance of this virus with pandemic potential and improve the control and treatment of infected patients.
Commercial Applications
May be licensed to commercial entities to manufacture and sell commercial reagents to research and clinical laboratories.
Competitive Advantages
This assay allows for specific detection and characterization of North American lineage influenza A/H7 viruses with high sensitivity and specificity and will complement with CDC human Influenza Viruses Real-Time RT-PCR Detection and Characterization Panel to detect these viruses.
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