FY-2025 Top 20 Commercially Successful Inventions
| VACCINES & THERAPEUTICS | |||
| Rank | ||||
1 | SARS Cov-2 Vaccines | Graham, et al. | NIAID | |
2 | Prefusion RSV F Proteins for Vaccines | McLeallan, et al. | NIAID | |
3 | Nutritional Supplement to Treat Macular Degeneration | Ferris, et al. | NEI | |
| 4 | Intranasal Administration of Ketamine to Treat Depression | Zarate, et al. | NIMH | |
5 | Streptococcus Pneumoniae Vaccines | Beall, et al. | CDC | |
6 | Preconditioning Patients for Adoptive T Cell Therapy | Bot, et al. | NCI | |
7 | CAR T-cell Therapy for Multiple Myeloma | Kochenderfer, et al. | NCI | |
| 8 | Dengue Vaccines | Whitehead, et al. | NIAID | |
13 | Bicistronic CAR Cancer Therapy | Qin, et al. | NCI | |
15 | Chimeric Antigen Receptor Targeting B-Cells | Kochenderfer, et al. | NCI | |
16 | Novel CRISPR Enzymes and Systems | Koonin, et al. | NLM | |
18 | Chikungunya Vaccines | Nabel, et al. | NIAID | |
19 | Contraceptive Methods | Ulman, et al. | NICHD | |
20 | Adoptive Immunotherapy with Enhanced TIL Cells | Gros, et al. | NCI | |
| DIAGNOSTICS | |||
| Rank | ||||
| 9 | DNA Probe for Breast Cancer Diagnosis (HER-2) | King, et al. | NCI | |
| 10 | HIV-1 Diagnostic Test Kits | Gallo, et all. | NCI | |
| INSTRUMENTATION & DEVICES | |||
| Rank | ||||
| 12 | Patch for Retinal Degenerative Disease | Bharti, et al. | NEI | |
| 17 | Transcranial Magnetic Stimulation System | Zangen, et al. | NIDA, NINDS | |
| RESEARCH MATERIALS & SERVICES | |||
| Rank | ||||
11 | Cell Lines Established from Certain Human Tumors | Oie, et al. | NCI | |
| 14 | NIH OVCAR Cell Lines | Hamilton, et al. | NCI | |
