Technology ID
TAB-771
Recombinant Plasmids for Soluble Immunoreceptors
E-Numbers
E-305-2003-0
Lead IC
NIAID
Co-Inventors
Sun, Peter
ICs
NIAID
Applications
Research Materials
Immunoreceptors initiate signals leading to the activation of immune system against invasion pathogens. A number of soluble receptors, representing the extracellular ligand binding domains of the immunoreceptors, have been expressed using a recombinant bacteria expression and reconstitution system. This set of 21 plasmids, which can be used as immunological research reagents or to develop diagnostic tools, comprise the following:
| Plasmid | Description |
| CD16-28b | Soluble CD16 |
| CD94 (S34) - 30a | Soluble CD94 truncated at S34 |
| CD94 (E51) - 30a | Soluble CD94 truncated at E51 |
| NKG2A (109R) - 30a | Soluble NKG2A 109R construct |
| NKG2A (117G) - 30a | Soluble NKG2A 117G construct |
| TBRII-30a | Soluble type II TGF-beta receptor |
| C143-30a | Soluble KIR2DL2 receptor |
| NKG2D-22b | Soluble NKG2D receptor |
| ULBP-1-22-b | Soluble ULBP-1 |
| ULBP-2-22-b | Soluble ULBP-2 |
| ULBP-3-22b | Soluble ULBP-3 |
| HLA-E-30a | Soluble HLA-E heavy chain |
| HLA-Cw3 | Soluble HLA-Cw3 heavy chain |
| TREM-1-22b | Soluble TREM-1 receptor |
| TREM-2-22b | Soluble TREM-2 receptor |
| NKp30-22b | Soluble NKp30 |
| NKp46-22b | Soluble NKp46 |
| NKp44-22b | Soluble NKp44 |
| Siglec-3-30a | Soluble Siglec-3 |
| Siglec-5-30a | Soluble Siglec-5 |
| Siglec-7-30a | Soluble Siglec-7 |
Licensing Contact: