Technology ID
TAB-2701
Nucleic Acid-based Compositions and Methods for the Detection of Pathogenic Candida or Aspergillus Fungi Species
E-Numbers
E-339-2013-0
Lead Inventor
Morrison, Christine
Lead IC
CDC
Co-Inventors
Reiss, Errol
Holloway, Brian
Shin, Jong
ICs
CDC
Applications
Therapeutics
Research Materials
Occupational Safety and Health
Diagnostics
Consumer Products
Therapeutic Areas
Ophthalmology
Oncology
Infectious Disease
Endocrinology
Dental
Cardiology
Development Stages
Pre-Clinical (in vitro)
Development Status
In vitro data available
This invention pertains to the development of oligonucleotides for the rapid nucleic acid-based identification of Candida or Aspergillus fungi species in biological samples. This identification is accomplished by the targeting the internally transcribed spacer-2 (ITS2) region that are unique to various Candida species. The assay is sensitive, specific and rapid. Implementation of the technology will facilitate earlier specific diagnoses, and lead to better antifungal therapy implementation for infected patients.
Commercial Applications
- Directing antifungal drug therapy for improved patient outcomes
- Detection, discrimination of Candida and Aspergillus species from biological samples
- Addressing secondary infections of immunosuppressed individuals
Competitive Advantages
- Easily adapted for use in kits
- High-throughput capable
- Rapid and cost-effective
Licensing Contact: